{"id":2566,"date":"2026-04-10T10:51:47","date_gmt":"2026-04-10T03:51:47","guid":{"rendered":"https:\/\/news.eloqasia.com\/?p=2566"},"modified":"2026-08-27T10:59:52","modified_gmt":"2026-08-27T03:59:52","slug":"hoi-nghi-khoa-hoc-ky-nguyen-moi-trong-dieu-tri-hen-va-benh-phoi-tac-nghen-man-tinh-copd-tu-huong-dan-dieu-tri-den-ung-dung-trong-thuc-hanh-lam-sang","status":"publish","type":"post","link":"https:\/\/news.eloqasia.com\/?p=2566","title":{"rendered":"H\u1ed9i ngh\u1ecb khoa h\u1ecdc: K\u1ef7 nguy\u00ean m\u1edbi trong \u0111i\u1ec1u tr\u1ecb Hen v\u00e0 B\u1ec7nh ph\u1ed5i t\u1eafc ngh\u1ebdn m\u1ea1n t\u00ednh (COPD) – T\u1eeb h\u01b0\u1edbng d\u1eabn \u0111i\u1ec1u tr\u1ecb \u0111\u1ebfn \u1ee9ng d\u1ee5ng trong th\u1ef1c h\u00e0nh l\u00e2m s\u00e0ng"},"content":{"rendered":"

V\u00e0o 2 ng\u00e0y 29\/3 v\u00e0 5\/4 t\u1ea1i Tp. H\u00e0 N\u1ed9i v\u00e0 H\u1ed3 Ch\u00ed Minh<\/b> \u2013 H\u1ed9i H\u00f4 h\u1ea5p Vi\u1ec7t Nam \u0111\u1ed3ng h\u00e0nh c\u00f9ng AstraZeneca Vi\u1ec7t Nam t\u1ed5 ch\u1ee9c H\u1ed9i ngh\u1ecb khoa h\u1ecdc v\u1edbi ch\u1ee7 \u0111\u1ec1 <\/span>“K\u1ef7 nguy\u00ean m\u1edbi trong \u0111i\u1ec1u tr\u1ecb hen v\u00e0 b\u1ec7nh ph\u1ed5i t\u1eafc ngh\u1ebdn m\u1ea1n t\u00ednh (COPD)” <\/b>. S\u1ef1 ki\u1ec7n c\u00f3 s\u1ef1 tham gia v\u00e0 chia s\u1ebb t\u1eeb GS.TS.BS Ng\u00f4 Qu\u00fd Ch\u00e2u, Ch\u1ee7 t\u1ecbch H\u1ed9i H\u00f4 H\u1ea5p Vi\u1ec7t Nam, PGS.TS.BS Tr\u1ea7n V\u0103n Ng\u1ecdc, Ch\u1ee7 t\u1ecbch H\u1ed9i H\u00f4 h\u1ea5p TP.HCM, Ph\u00f3 Ch\u1ee7 t\u1ecbch H\u1ed9i Ph\u1ed5i Vi\u1ec7t Nam, c\u00e1c chuy\u00ean gia \u0111\u1ea7u ng\u00e0nh, y b\u00e1c s\u0129, d\u01b0\u1ee3c s\u0129 l\u00e2m s\u00e0ng t\u1eeb kh\u1eafp m\u1ecdi mi\u1ec1n \u0111\u1ea5t n\u01b0\u1edbc, \u00f4ng Atul Tandon \u2013 Ch\u1ee7 t\u1ecbch ki\u00eam T\u1ed5ng Gi\u00e1m \u0111\u1ed1c Astra Zeneca Vi\u1ec7t Nam. H\u1ed9i ngh\u1ecb kh\u00f4ng ch\u1ec9 c\u1eadp nh\u1eadt nh\u1eefng ti\u1ebfn b\u1ed9 y khoa m\u00e0 c\u00f2n l\u00e0 n\u01a1i chia s\u1ebb v\u1ec1 c\u00e1c ki\u1ebfn th\u1ee9c l\u00e2m s\u00e0ng th\u1ef1c ti\u1ec5n v\u1ec1 c\u00e1c gi\u1ea3i ph\u00e1p ph\u00f2ng ng\u1eeba, qu\u1ea3n l\u00fd v\u00e0 \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3 c\u00e1c b\u1ec7nh l\u00fd h\u00f4 h\u1ea5p m\u1ea1n t\u00ednh t\u1ea1i Vi\u1ec7t Nam.<\/span><\/p>\n

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Trong nhi\u1ec1u th\u1eadp k\u1ef7 qua, b\u1ec7nh l\u00fd h\u00f4 h\u1ea5p m\u1ea1n t\u00ednh v\u1eabn lu\u00f4n l\u00e0 nh\u1eefng “qu\u1ea3 bom h\u1eb9n gi\u1edd”, \u00e2m th\u1ea7m b\u00e0o m\u00f2n s\u1ee9c kh\u1ecfe ng\u01b0\u1eddi b\u1ec7nh v\u00e0 t\u1ea1o ra nhi\u1ec1u \u00e1p l\u1ef1c l\u00ean h\u1ec7 th\u1ed1ng y t\u1ebf. H\u1ed9i ngh\u1ecb l\u1ea7n n\u00e0y mang \u00fd ngh\u0129a b\u01b0\u1edbc ngo\u1eb7t khi ch\u00ednh th\u1ee9c gi\u1edbi thi\u1ec7u nh\u1eefng c\u1eadp nh\u1eadt chi\u1ebfn l\u01b0\u1ee3c m\u1edbi nh\u1ea5t t\u1eeb th\u1ebf gi\u1edbi, t\u00e1i \u0111\u1ecbnh h\u00ecnh ho\u00e0n to\u00e0n m\u1ee5c ti\u00eau \u0111i\u1ec1u tr\u1ecb: t\u1eeb vi\u1ec7c ch\u1ec9 ki\u1ec3m so\u00e1t tri\u1ec7u ch\u1ee9ng \u0111\u01a1n thu\u1ea7n sang ch\u1ee7 \u0111\u1ed9ng ph\u00f2ng ng\u1eeba \u0111\u1ee3t c\u1ea5p, b\u1ea3o v\u1ec7 ch\u1ee9c n\u0103ng tim ph\u1ed5i v\u00e0 tr\u1ef1c ti\u1ebfp l\u00e0m gi\u1ea3m t\u1ef7 l\u1ec7 t\u1eed vong.<\/span><\/p>\n

G\u00e1nh n\u1eb7ng c\u1ee7a COPD: Nguy\u00ean nh\u00e2n t\u1eed vong h\u00e0ng th\u1ee9 3 v\u00e0 m\u1ed1i li\u00ean k\u1ebft v\u1edbi c\u00e1c b\u1ec7nh l\u00fd tim ph\u1ed5i<\/b><\/p>\n

Tr\u00ean to\u00e0n th\u1ebf gi\u1edbi, b\u1ec7nh ph\u1ed5i t\u1eafc ngh\u1ebdn m\u1ea1n t\u00ednh (COPD) \u0111ang t\u1ea1o ra nh\u1eefng \u00e1p l\u1ef1c y t\u1ebf v\u00e0 kinh t\u1ebf to l\u1edbn. C\u0103n b\u1ec7nh n\u00e0y g\u00e2y \u1ea3nh h\u01b0\u1edfng t\u1edbi 390 tri\u1ec7u ng\u01b0\u1eddi v\u00e0 \u0111\u00e3 l\u1ea5y \u0111i sinh m\u1ea1ng c\u1ee7a h\u01a1n 3 tri\u1ec7u ng\u01b0\u1eddi m\u1ed7i n\u0103m. Ri\u00eang t\u1ea1i Vi\u1ec7t Nam, COPD hi\u1ec7n l\u00e0 nguy\u00ean nh\u00e2n g\u00e2y t\u1eed vong \u0111\u1ee9ng th\u1ee9 3 v\u1edbi h\u01a1n 25.000 ca t\u1eed vong m\u1ed7i n\u0103m, cao h\u01a1n t\u1eed vong do tai n\u1ea1n giao th\u00f4ng [1]. \u0110\u00e1ng b\u00e1o \u0111\u1ed9ng h\u01a1n, c\u00f3 \u0111\u1ebfn kho\u1ea3ng 65-80% b\u1ec7nh nh\u00e2n COPD trong c\u1ed9ng \u0111\u1ed3ng ch\u01b0a \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n, khi\u1ebfn h\u1ecd b\u1ecf l\u1ee1 “th\u1eddi \u0111i\u1ec3m v\u00e0ng” \u0111\u1ec3 can thi\u1ec7p s\u1edbm v\u00e0 ng\u0103n ch\u1eb7n t\u1ed5n th\u01b0\u01a1ng ph\u1ed5i kh\u00f4ng th\u1ec3 ph\u1ee5c h\u1ed3i [2].<\/span><\/p>\n

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Trong b\u1ee9c tranh d\u1ecbch t\u1ec5 \u0111\u00f3, c\u00e1c \u0111\u1ee3t c\u1ea5p COPD kh\u00f4ng ch\u1ec9 l\u00e0 s\u1ef1 suy gi\u1ea3m h\u00f4 h\u1ea5p t\u1ea1m th\u1eddi m\u00e0 th\u1ef1c s\u1ef1 l\u00e0 nh\u1eefng bi\u1ebfn c\u1ed1 \u0111e d\u1ecda tr\u1ef1c ti\u1ebfp \u0111\u1ebfn t\u00ednh m\u1ea1ng. D\u1eef li\u1ec7u l\u00e2m s\u00e0ng \u0111\u00e3 cho th\u1ea5y m\u1ed9t th\u1ef1c t\u1ebf \u0111\u00e1ng lo ng\u1ea1i: c\u00f3 kho\u1ea3ng 50% b\u1ec7nh nh\u00e2n s\u1ed1ng s\u00f3t sau 3,6 n\u0103m k\u1ec3 t\u1eeb \u0111\u1ee3t c\u1ea5p n\u1eb7ng \u0111\u1ea7u ti\u00ean [3]. \u0110i\u1ec1u n\u00e0y \u0111\u1ed3ng ngh\u0129a v\u1edbi vi\u1ec7c \u0111\u1ee3t c\u1ea5p COPD mang ti\u00ean l\u01b0\u1ee3ng x\u1ea5u t\u01b0\u01a1ng \u0111\u01b0\u01a1ng, th\u1eadm ch\u00ed c\u00f2n x\u1ea5u h\u01a1n m\u1ed9t s\u1ed1 b\u1ec7nh l\u00fd ung th\u01b0 ph\u1ed5 bi\u1ebfn.<\/span><\/p>\n

H\u01a1n th\u1ebf n\u1eefa, m\u1ed9t trong nh\u1eefng \u0111i\u1ec3m nh\u1ea5n quan tr\u1ecdng nh\u1ea5t \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 t\u1ea1i H\u1ed9i ngh\u1ecb l\u00e0 m\u1ed1i li\u00ean h\u1ec7 gi\u1eefa COPD v\u1edbi bi\u1ebfn c\u1ed1 tim ph\u1ed5i. Khi b\u1ec7nh nh\u00e2n COPD tr\u1ea3i qua c\u00e1c tri\u1ec7u ch\u1ee9ng di\u1ec5n ti\u1ebfn x\u1ea5u v\u00e0 r\u01a1i v\u00e0o \u0111\u1ee3t c\u1ea5p, t\u0103ng t\u00ecnh tr\u1ea1ng vi\u00eam to\u00e0n th\u00e2n , d\u1eabn \u0111\u1ebfn c\u00e1c bi\u1ebfn c\u1ed1 tim ph\u1ed5i v\u00e0 c\u00f3 th\u1ec3 g\u00e2y t\u1eed vong s\u1edbm. B\u1ec7nh nh\u00e2n b\u1ecb t\u0103ng nguy c\u01a1 bi\u1ebfn c\u1ed1 tim m\u1ea1ch l\u00ean \u0111\u1ebfn 3,8 l\u1ea7n ch\u1ec9 trong v\u00f2ng 30 ng\u00e0y \u0111\u1ea7u ti\u00ean sau khi x\u1ea3y ra \u0111\u1ee3t c\u1ea5p, v\u00e0 nguy c\u01a1 n\u00e0y v\u1eabn c\u00f2n cao cho \u0111\u1ebfn tr\u1ecdn 1 n\u0103m sau \u0111\u00f3 [4]. Nh\u1eefng con s\u1ed1 bi\u1ebft n\u00f3i n\u00e0y cho th\u1ea5y \u0111\u1ee3t c\u1ea5p COPD ch\u00ednh l\u00e0 \u201cy\u1ebfu t\u1ed1 kh\u1edfi ph\u00e1t\u201d tr\u1ef1c ti\u1ebfp cho c\u00e1c bi\u1ebfn c\u1ed1 tim m\u1ea1ch nghi\u00eam tr\u1ecdng nh\u01b0 nh\u1ed3i m\u00e1u c\u01a1 tim hay \u0111\u1ed9t qu\u1ef5. Theo m\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u kh\u00e1c tr\u00ean th\u1ebf gi\u1edbi cho th\u1ea5y c\u00f3 kho\u1ea3ng 35%\u201340% tr\u01b0\u1eddng h\u1ee3p t\u1eed vong l\u00e0 do c\u00e1c bi\u1ebfn ch\u1ee9ng tim m\u1ea1ch, bao g\u1ed3m suy tim, b\u1ec7nh x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch, r\u1ed1i lo\u1ea1n nh\u1ecbp tim v\u00e0 \u0111\u1ed9t t\u1eed [4].<\/span><\/p>\n

B\u00ean c\u1ea1nh s\u1ef1 suy gi\u1ea3m v\u1ec1 th\u1ec3 ch\u1ea5t, COPD c\u00f2n t\u1ea1o ra g\u00e1nh n\u1eb7ng l\u1edbn v\u1ec1 kinh t\u1ebf v\u00e0 x\u00e3 h\u1ed9i, b\u00e0o m\u00f2n n\u0103ng su\u1ea5t lao \u0111\u1ed9ng. Kho\u1ea3ng 40% ng\u01b0\u1eddi b\u1ec7nh bu\u1ed9c ph\u1ea3i gi\u1ea3m kh\u1ed1i l\u01b0\u1ee3ng c\u00f4ng vi\u1ec7c ho\u1eb7c ng\u1eebng l\u00e0m vi\u1ec7c ho\u00e0n to\u00e0n[5]. \u1ede g\u00f3c \u0111\u1ed9 \u0111\u1eddi s\u1ed1ng, b\u1ec7nh nh\u00e2n d\u1ea7n \u0111\u00e1nh m\u1ea5t s\u1ef1 \u0111\u1ed9c l\u1eadp, ph\u1ea3i ph\u1ee5 thu\u1ed9c v\u00e0o gia \u0111\u00ecnh trong c\u00e1c sinh ho\u1ea1t c\u01a1 b\u1ea3n v\u00e0 b\u1ecb h\u1ea1n ch\u1ebf kh\u1ea3 n\u0103ng \u0111i l\u1ea1i<\/span><\/p>\n

C\u1eadp nh\u1eadt t\u1eeb H\u01b0\u1edbng d\u1eabn to\u00e0n c\u1ea7u GOLD 2026: Thay \u0111\u1ed5i m\u00f4 h\u00ecnh can thi\u1ec7p<\/b><\/p>\n

D\u1ef1a tr\u00ean nh\u1eefng b\u1eb1ng ch\u1ee9ng l\u00e2m s\u00e0ng thuy\u1ebft ph\u1ee5c, GOLD 2025-2026 \u0111\u00e3 \u0111\u01b0a ra nh\u1eefng thay \u0111\u1ed5i mang t\u00ednh c\u00e1ch m\u1ea1ng trong ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb. C\u00e1c chuy\u00ean gia t\u1ea1i h\u1ed9i ngh\u1ecb \u0111\u00e3 ph\u00e2n t\u00edch v\u1ec1 s\u1ef1 nguy hi\u1ec3m c\u1ee7a c\u00e1c \u0111\u1ee3t c\u1ea5p \u1edf ng\u01b0\u1eddi b\u1ec7nh: M\u1ed9t \u0111\u1ee3t c\u1ea5p m\u1ee9c \u0111\u1ed9 trung b\u00ecnh x\u1ea3y ra trong v\u00f2ng m\u1ed9t n\u0103m tr\u01b0\u1edbc khi b\u1ec7nh nh\u00e2n ch\u00ednh th\u1ee9c \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n COPD \u0111\u00e3 l\u00e0m t\u0103ng \u00a0 nguy c\u01a1 x\u1ea3y ra c\u00e1c \u0111\u1ee3t c\u1ea5p ti\u1ebfp theo [6].<\/span><\/p>\n

H\u1ed9i th\u1ea3o n\u00e0y c\u0169ng c\u1eadp nh\u1eadt th\u00f4ng tin v\u1ec1 \u0110\u1ed3ng thu\u1eadn c\u1ee7a H\u1ed9i H\u00f4 h\u1ea5p v\u00e0 H\u1ed9i tim m\u1ea1ch Vi\u1ec7t Nam v\u1ec1 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n COPD \u0111\u1ed3ng m\u1eafc tim m\u1ea1ch, \u0111\u00e1nh d\u1ea5u s\u1ef1 ph\u1ed1i h\u1ee3p li\u00ean chuy\u00ean khoa trong qu\u1ea3n l\u00fd v\u00e0 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n COPD v\u00e0 b\u1ec7nh nh\u00e2n tim m\u1ea1ch.<\/span><\/p>\n

Tr\u00ean c\u01a1 s\u1edf nguy c\u01a1 tim m\u1ea1ch gia t\u0103ng r\u00f5 r\u1ec7t trong v\u00e0 sau \u0111\u1ee3t c\u1ea5p, t\u1ea7m quan tr\u1ecdng c\u1ee7a vi\u1ec7c ph\u00f2ng ng\u1eeba \u0111\u1ee3t c\u1ea5p COPD nay \u0111\u01b0\u1ee3c n\u00e2ng l\u00ean th\u00e0nh m\u1ed9t trong nh\u1eefng m\u1ee5c ti\u00eau c\u1ea7n \u0111\u1ea1t \u0111\u01b0\u1ee3c . \u0110\u1ec3 gi\u1ea3i quy\u1ebft b\u00e0i to\u00e1n n\u00e0y, GOLD 2026 ch\u00ednh th\u1ee9c khuy\u1ebfn c\u00e1o vi\u1ec7c s\u1eed d\u1ee5ng li\u1ec7u ph\u00e1p b\u1ed9 ba nh\u01b0 l\u00e0 ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb n\u1ed1i ti\u1ebfp ti\u00eau chu\u1ea9n cho b\u1ec7nh nh\u00e2n c\u00f3 t\u1eeb 1 \u0111\u1ee3t c\u1ea5p tr\u1edf l\u00ean trong v\u00f2ng 12 th\u00e1ng qua, v\u00e0 c\u00f3 s\u1ed1 l\u01b0\u1ee3ng b\u1ea1ch c\u1ea7u \u00e1i toan l\u1edbn >=300 t\u1ebf b\u00e0o\/mcl.<\/span><\/p>\n

\u0110\u1eb7c bi\u1ec7t, h\u1ed9i ngh\u1ecb nh\u1ea5n m\u1ea1nh t\u1ea7m quan tr\u1ecdng c\u1ee7a khuy\u1ebfn c\u00e1o n\u00e0y: Li\u1ec7u ph\u00e1p b\u1ed9 ba hi\u1ec7n l\u00e0 \u0111i\u1ec1u tr\u1ecb d\u00f9ng thu\u1ed1c c\u00f3 b\u1eb1ng ch\u1ee9ng l\u00e2m s\u00e0ng v\u1eefng ch\u1eafc gi\u1ea3m t\u1ef7 l\u1ec7 t\u1eed vong tr\u00ean b\u1ec7nh nh\u00e2n COPD [7]. B\u00ean c\u1ea1nh hi\u1ec7u qu\u1ea3 y khoa, vi\u1ec7c t\u00edch h\u1ee3p ba th\u00e0nh ph\u1ea7n thu\u1ed1c v\u00e0o trong 1 d\u1ee5ng c\u1ee5 h\u00edt duy nh\u1ea5t mang l\u1ea1i s\u1ef1 thu\u1eadn ti\u1ec7n, n\u00e2ng cao hi\u1ec7u qu\u1ea3 ph\u00e2n ph\u1ed1i thu\u1ed1c v\u00e0o ph\u1ed5i. \u0110i\u1ec1u n\u00e0y c\u1ea3i thi\u1ec7n r\u00f5 r\u1ec7t s\u1ef1 tu\u00e2n th\u1ee7 \u0111i\u1ec1u tr\u1ecb c\u1ee7a b\u1ec7nh nh\u00e2n so v\u1edbi vi\u1ec7c ph\u1ea3i s\u1eed d\u1ee5ng nhi\u1ec1u d\u1ee5ng c\u1ee5 h\u00edt r\u1eddi r\u1ea1c, \u0111\u1eb7c bi\u1ec7t ph\u00f9 h\u1ee3p \u0111\u1ec3 tri\u1ec3n khai qu\u1ea3n l\u00fd b\u1ec7nh nh\u00e2n m\u1ea1n t\u00ednh t\u1ea1i tuy\u1ebfn y t\u1ebf c\u01a1 s\u1edf.<\/span><\/p>\n

K\u1ef7 nguy\u00ean m\u1edbi trong qu\u1ea3n l\u00fd Hen: M\u1ee5c ti\u00eau kh\u00f4ng \u0111\u1ee3t c\u1ea5p v\u00e0 ki\u1ec3m so\u00e1t to\u00e0n di\u1ec7n<\/b><\/p>\n

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Hen ph\u1ebf qu\u1ea3n l\u00e0 b\u1ec7nh h\u00f4 h\u1ea5p m\u1ea1n t\u00ednh ph\u1ed5 bi\u1ebfn t\u1ea1i Vi\u1ec7t Nam, v\u1edbi t\u1ef7 l\u1ec7 m\u1eafc kho\u1ea3ng 4,1% d\u00e2n s\u1ed1 [8]. Tuy nhi\u00ean, t\u1ef7 l\u1ec7 b\u1ec7nh nh\u00e2n ch\u01b0a \u0111\u1ea1t ki\u1ec3m so\u00e1t v\u1eabn \u1edf m\u1ee9c cao t\u1ea1i Vi\u1ec7t Nam c\u0169ng nh\u01b0 nhi\u1ec1u qu\u1ed1c gia ch\u00e2u \u00c1 [9], k\u00e9o theo s\u1ef1 gia t\u0103ng c\u00e1c ca nh\u1eadp vi\u1ec7n v\u00e0 c\u1ea5p c\u1ee9u do \u0111\u1ee3t k\u1ecbch ph\u00e1t. G\u00e1nh n\u1eb7ng n\u00e0y kh\u00f4ng ch\u1ec9 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ch\u1ee9c n\u0103ng h\u00f4 h\u1ea5p m\u00e0 c\u00f2n g\u00e2y t\u1ed5n th\u1ea5t \u0111\u00e1ng k\u1ec3 v\u1ec1 kinh t\u1ebf \u2013 x\u00e3 h\u1ed9i.<\/span><\/p>\n

\u0110\u00e1ng ch\u00fa \u00fd, nh\u00f3m b\u1ec7nh nh\u00e2n hen n\u1eb7ng, d\u00f9 chi\u1ebfm t\u1ef7 l\u1ec7 nh\u1ecf, l\u1ea1i c\u00f3 nguy c\u01a1 nh\u1eadp vi\u1ec7n cao g\u1ea5p 10 l\u1ea7n [10] v\u00e0 ti\u00eau t\u1ed1n l\u00ean t\u1edbi 60% ngu\u1ed3n l\u1ef1c kinh t\u1ebf [11]. Trong th\u1ef1c h\u00e0nh, \u0111i\u1ec1u tr\u1ecb truy\u1ec1n th\u1ed1ng ch\u1ee7 y\u1ebfu d\u1eebng l\u1ea1i \u1edf ki\u1ec3m so\u00e1t tri\u1ec7u ch\u1ee9ng, trong khi nhi\u1ec1u b\u1ec7nh nh\u00e2n v\u1eabn ph\u1ea3i ph\u1ee5 thu\u1ed9c v\u00e0o corticoid \u0111\u01b0\u1eddng u\u1ed1ng (OCS), k\u00e9o theo nguy c\u01a1 bi\u1ebfn ch\u1ee9ng \u0111a c\u01a1 quan nh\u01b0 lo\u00e3ng x\u01b0\u01a1ng, \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, tim m\u1ea1ch v\u00e0 \u0111\u1ee5c th\u1ee7y tinh th\u1ec3 [12]. C\u00e1c li\u1ec7u ph\u00e1p sinh h\u1ecdc tr\u01b0\u1edbc \u0111\u00e2y, v\u1edbi c\u01a1 ch\u1ebf \u1ee9c ch\u1ebf c\u00e1c \u0111\u01b0\u1eddng vi\u00eam h\u1ea1 ngu\u1ed3n ri\u00eang l\u1ebb, d\u00f9 mang l\u1ea1i hi\u1ec7u qu\u1ea3 \u1edf m\u1ed9t s\u1ed1 nh\u00f3m b\u1ec7nh nh\u00e2n, nh\u01b0ng v\u1eabn c\u00f2n h\u1ea1n ch\u1ebf trong b\u1ed1i c\u1ea3nh th\u1ef1c t\u1ebf t\u1ea1i Vi\u1ec7t Nam khi vi\u1ec7c x\u00e1c \u0111\u1ecbnh ch\u00ednh x\u00e1c ki\u1ec3u h\u00ecnh hen \u0111\u1eb7c bi\u1ec7t l\u00e0 ki\u1ec3u h\u00ecnh h\u1ed7n h\u1ee3p ch\u01b0a lu\u00f4n kh\u1ea3 thi.<\/span><\/p>\n

Tr\u01b0\u1edbc b\u1ed1i c\u1ea3nh \u0111\u00f3, m\u1ed9t h\u01b0\u1edbng ti\u1ebfp c\u1eadn m\u1edbi \u0111ang \u0111\u01b0\u1ee3c th\u00fac \u0111\u1ea9y: can thi\u1ec7p s\u1edbm v\u00e0o c\u01a1 ch\u1ebf vi\u00eam n\u1ec1n t\u1ea3ng ngay t\u1eeb \u201cth\u01b0\u1ee3ng ngu\u1ed3n\u201d. \u0110i\u1ec3n h\u00ecnh, li\u1ec7u ph\u00e1p nh\u1eafm v\u00e0o TSLP m\u1ed9t cytokine ch\u1ee7 ch\u1ed1t kh\u1edfi ph\u00e1t nhi\u1ec1u d\u00f2ng th\u00e1c vi\u00eam, cho th\u1ea5y kh\u1ea3 n\u0103ng ki\u1ec3m so\u00e1t gi\u00fap ki\u1ec3m so\u00e1t \u0111\u1ee3t k\u1ecbch ph\u00e1t tr\u00ean nhi\u1ec1u ki\u1ec3u h\u00ecnh hen bao g\u1ed3m c\u1ea3 c\u00e1c tr\u01b0\u1eddng h\u1ee3p kh\u00f3 ph\u00e2n lo\u1ea1i trong th\u1ef1c h\u00e0nh v\u00e0 t\u1ed1i thi\u1ec3u h\u00f3a s\u1eed d\u1ee5ng OCS. C\u00e1ch ti\u1ebfp c\u1eadn n\u00e0y m\u1edf ra kh\u1ea3 n\u0103ng \u0111\u1ea1t \u0111\u01b0\u1ee3c m\u1ee5c ti\u00eau \u0111i\u1ec1u tr\u1ecb trong k\u1ef7 nguy\u00ean m\u1edbi, d\u1ef1a tr\u00ean hai tr\u1ee5 c\u1ed9t c\u1ed1t l\u00f5i:<\/span><\/p>\n